service - MicroED
B A C KBridging the Gap in Crystal Size
MicroED is a new technology, which uses electron as incident beam to obtain MicroED microcrystalline electron diffraction data on Croy-TEM.
Electrons interact with matter more strongly than X-rays. This means that MicroED may be used to solve structures from vanishingly small crystals（100–300 nm）, but also implies that larger crystals (>1 um thick) cannot be efficiently penetrated by the electron beam. Alleviating the need for long and complicated large-crystal growth, MicroED is amenable to examine much smaller crystals that are one billionth the size typically needed for X-ray crystallography.
MicroED Workflow
Why choose ShuimuBio for MicroED?
MicroED fills critical gaps in existing methods and expands the application of cryo-EM. Our MicroED patform provides high resolution structures for challenging small molecule, peptide and macromolecular samples. Among the completed projects，atomic details can be extracted from individual nanocrystals in minutes, sufficiently high signal-to-noise ratio diffraction signal can be produced and 3D structure can be elucidated at atomic resolution.
Why do you need MicroED Services?
● Material is extremely limited
● Samples exhibit poor crystallization behavior
● Avoidance of hand-pick individual crystals
About the samples
Crystals Size:
100–300 nm